Apuckshunubbee (ca. 1740–October 18, 1824) was one of three principal chiefs of the Choctaw Native American tribe in the early nineteenth century, from before 1800. He led the western or Okla Falaya (Tall People) District in present-day Mississippi. There were also the eastern and southern districts.
During the early 1800s, Apuckshunubbee and the other two division chiefs signed several treaties with the United States, ceding land to settlers in the hope of ending their encroachment on Choctaw territory. On his way to Washington, DC in 1824 with the other two division chiefs and a Choctaw delegation to meet with US officials, Apukshunubbee suffered a fall and died. His name was also spelled as Apvkshvnvbbee, Apυkshυnυbbee, Puckshenubbee, Pukshunnubbu, and Pukshunnubbee.
Apuckshunubbee was likely born into a high-status family and clan; the Choctaw had a matrilineal system of property and hereditary leadership. Children belonged to their mother's clan, and her brothers would have been more important to his upbringing than his biological father, who belonged to a different clan.