Francis Mansour Zayek (October 18, 1920 – September 14, 2010) was an American Maronite Catholic prelate. Zayek was the founding bishop of the Eparchy of Saint Maron of Brooklyn, a diocese based in Brooklyn, New York covering the Maronite Church in the United States.
Zayek was one of the last surviving bishops who had attended all four sessions of the Second Vatican Council between 1962 and 1965 as a bishop.
Zayek was born in Manzanillo, Cuba, on October 18, 1920. He emigrated with his family from Cuba to Lebanon, then part of the French Mandate for Syria and the Lebanon, in 1931. He studied at seminaries in both Lebanon and Rome, before being ordained a Maronite Catholic priest in Rome, Italy, on March 17, 1946.
Zayek received a doctorate in canon law from a school in Rome. Soon after completing his doctorate, Zayek was appointed to serve in the apostolic nunciature in Cairo, Egypt. He returned to Rome, where he worked at the Roman Rota.
Zayek was appointed the Bishop of the Maronite Church in Brazil on May 31, 1962, by Pope John XXIII. He was formally consecrated bishop at a ordination ceremony held in Dimane, Lebanon, on August 5, 1962.