Regino José Otero Gómez (September 7, 1915, Havana, Cuba – October 21, 1988, Hialeah, Florida) was a Cuban baseball player who had a long career in the minor leagues in the United States (1936–1953), and played briefly with the Chicago Cubs in 1945. He also played 13 years in the Cuban Professional League. He was a left-handed batter, but threw right-handed. After his playing career ended, he managed in Cuba, Mexico and Venezuela.
Reggie Otero made his organized baseball debut in 1936 with the York White Roses/Trenton Senators club of the New York-Penn League, where he hit .243 with 0 home runs and 22 RBI. He also played for the International League's Albany Senators that year, but hit only .111. The following year he returned to the Senators but still had trouble, hitting .136 with 0 HR and 3 RBI. In 1938 he moved south to the St. Augustine Saints (Florida State League). There he hit .308, still with 0 HR, but with 52 RBI.
Otero played for the Greenville Spinners in 1939 and 1940. In his two seasons in the South Atlantic League he hit .325-2-57 and then .315-1-50. He moved back north in 1941, when he played for the Springfield Nationals of the Eastern League and hit .223-0-24.